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Titre :
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The gendered impact of coronavirus disease (COVID-19) : do estrogens play a role? (2020)
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Auteurs :
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G. GRANDI, Auteur ;
F. FACCHINETTI, Auteur ;
J. BITZER, Auteur
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Type de document :
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Article : Article de périodique
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Dans :
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EUROPEAN JOURNAL OF CONTRACEPTION & REPRODUCTIVE HEALTH CARE (THE) (Vol. 25 - N° 3, June 2020)
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Article en page(s) :
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pp.233-234
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Langues:
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Anglais
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Index. décimale :
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231 (Contraception hormonale)
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Catégories :
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CONTRACEPTION HORMONALE
COVID-19
EFFETS IATROGENES
EFFETS SECONDAIRES
EFFETS THERAPEUTIQUES
FEMMES
HOMMES
HORMONES
SEX-RATIO
SEXE
SYSTEME IMMUNITAIRE
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Résumé :
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Although sex-disaggregated data for COVID-19 show equal numbers of cases between men and women, there seem to be sex differences in mortality rate and vulnerability to the disease : more men than women are dying. The authors have explored the potential role of estrogens in this COVID-19 gendered impact. Estrogens stimulate the humoral response to viral infections, while testosterone and progesterone give an immune suppression of both innate and cell-mediated immune responses. The authors hypothesise that estrogens, in particular estradiol but also synthetic estrogen such as ethinylestradiol, could protect women from the most serious complications of COVID-19.
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